HORDB

ID: hor002629
Uniprot ID: O44540
Protein name: NLP-13
Gene name: nlp-13
Organism: Caenorhabditis elegans
Family: NA
Source: Animal
Expression: NA
Disease: NA
Comments: NA
Taxonomy: Caenorhabditis (genus), Peloderinae (subfamily), Rhabditidae (family), Rhabditoidea (superfamily), Rhabditomorpha (infraorder), Rhabditina (suborder), Rhabditida (order), Chromadorea (class), Nematoda (phylum), Ecdysozoa, Protostomia, Bilateria, Eumetazoa, Metazoa (kingdom), Opisthokonta, Eukaryota (superkingdom), cellular organisms
GO MF: NA
GO BP: GO:0007218 neuropeptide signaling pathway
GO CC: GO:0005576 extracellular region

Sequence: SSSMYDRDIMSF
Length: 12(93-104)
Propeptide: MQRSLQIFCIMSAIAMAYSQGSRDDNQSAKRNDFSRDIMSFGKRSGNTADLYDRRIMAFGKRQPSYDRDIMSFGKRSAPSDFSRDIMSFGKRSSSMYDRDIMSFGKRSPVDYDRPIMAFGKRAEDYERQIMAFGRRK
Signal peptide: MQRSLQIFCIMSAIAMAYS
Modification: NA
Glycosylation: NA
Mutagenesis: NA

Structure: (PDB_ID-from https://www.rcsb.org/; AlphaFold_DB_ID-from https://alphafold.ebi.ac.uk/; hordbxxxxxx_AF2.pdb was predicted structure by AlphaFold2; hordbxxxxxx_ESM.pdb was predicted structure by ESMFold)

hor002629_AF2.pdb

hor002629_ESM.pdb

Mass:	163496	Formula:	C60H91N15O22S2
Absent amino acids:	ACEGHKLNPQTVW	Common amino acids:	S
pI:	4.11	Basic residues:	1
Polar residues:	5	Hydrophobic residues:	2
Hydrophobicity:	-40.83	Boman Index:	-3350
Half-Life:	1.9 hour	Half-Life Yeast:	>20 hour
Half-Life E.Coli:	>10 hour	Aliphatic Index	32.5
Instability Index:	11106.67	Extinction Coefficient cystines:	1490
Absorbance 280nm:	135.45

PubMed ID: 20013198
Title: Approaches to Identify Endogenous Peptides in the Soil Nematode Caenorhabditis elegans